
Cinnamtannin A2
CAS No. 86631-38-1
Cinnamtannin A2 ( —— )
产品货号. M32135 CAS No. 86631-38-1
Cinnamtannin A2, a tetrameric procyanidin, enhances GLP-1 and insulin secretion in mice while also upregulating the expression of corticotrophin releasing hormone.
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥5194 | 有现货 |
![]() ![]() |
50MG | 获取报价 | 有现货 |
![]() ![]() |
100MG | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称Cinnamtannin A2
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Cinnamtannin A2, a tetrameric procyanidin, enhances GLP-1 and insulin secretion in mice while also upregulating the expression of corticotrophin releasing hormone.
-
产品描述Cinnamtannin A2, a tetrameric procyanidin, enhances GLP-1 and insulin secretion in mice while also upregulating the expression of corticotrophin releasing hormone. Additionally, Cinnamtannin A2 exhibits antioxidant, anti-diabetic, and nephroprotective effects.
-
体外实验Cinnamtannin A2 (0.125-2.0 μg/mL) inhibits LDL oxidation induced by copper ions or MeO-AMVN.
-
体内实验Cinnamtannin A2 (10 mg/kg; i.p. for 30 days) ameliorates the level of KIM1 and NAGL in 5/6 nephractomized rats by regulating Nrf2- Keap1 pathway.Cinnamtannin A2 (10 μg/kg; p.o.) increases the secretion of insulin and glucagon-like peptide-1 (GLP-1) in plasma of mice. Cinnamtannin A2 (10 μg/kg; p.o.) significantly promotes phosphorylation of both IRB and IRS-1 in mice. Animal Model:Male Sprague-Dawley rats (250-300 g) were induced chronic renal failure (CRF) by removing the kidneys Dosage:10 mg/kg Administration:I.p. for 30 days Result:Ameliorated the altered level of creatinine, blood urea nitrogen, Neutrophil gelatinase-associated lipocalin, Kidney Injury Molecule-1 and cytokines in the serum and microalbuminurea.Reduced the oxidative stress level.Attenuated the altered expression of proteins involved in Nrf2-Keap1 pathway in the kidney tissue.Reduced the tubular injury score in the kidney tissue.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number86631-38-1
-
分子量1155.1
-
分子式C60H50O24
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册




关联产品
-
Sodium bromide
溴化钠 [NaBr] 是一种卤化物抗惊厥化合物,用于兽医治疗癫痫。
-
1-[4-(2,3-dihydro-1,...
1-[4-(2,3-二氢-1,4-苯并二恶因-6-磺酰基)哌嗪-1-基]-2-(6-甲基-1-苯并呋喃-3-基)乙烷-1-酮是用作分子构件的化合物。
-
Spathulenol
Spathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway.